Cutaneous Leishmaniasis

Introduction : 

Cutaneous leishmaniasis (CL) is a parasitic infection caused by the Leishmania protozoa. It is transmitted to humans through the bites of infected female sandflies, primarily from the genus Phlebotomus in the Old World and Lutzomyia in the New World. The disease is prevalent in tropical and subtropical regions, including parts of South America, the Middle East, Central Asia, and Africa... Read more 

The life cycle of  Leishmania : 


Symptoms:

The disease primarily affects the skin and typically presents as skin lesions. The incubation period can vary from weeks to months after the sandfly bite. The initial skin lesion often starts as a small, painless papule or nodule at the site of the sandfly bite. Over time, it may grow larger and develop into an ulcer with raised edges and a central crater. The lesions can be single or multiple, and they may be disfiguring if left untreated.

                                                                             

CL Detect™ Rapid Test for Cutaneous Leishmaniasis

The CL Detect™ Rapid Test is a qualitative, in vitro immunochromatographic assay for the rapid detection of Leishmania species antigen in ulcerative skin lesions. The test is intended for use with dental broach samples from less than four month old ulcerative skin lesions that are obtained from patients with suspected cutaneous leishmaniasis (CL). 

The test targets the peroxidoxin antigen of Leishmania species that may cause CL.


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Internal Reference: YF-PA26408