Amendment to the Residual Solvent Test Method in the General Pharmaceutical Test Methods

On December 22, 2016, the MFDS issued an administrative notice  regarding a revised version of the Residual Solvent Testing Method in the General Pharmaceutical Testing Methods. Let's explore what the residual solvent testing method is and why residual solvent analysis and management are crucial.  Using Merck's Headspace solvent, Restek's residual solvent standards, and a dedicated residual solvent analysis column, you can achieve accurate quantitative analysis.

HPLC analysis of chlorogenic acid in apples using Puroshper STAR

Chlorogenic acid, a type of antioxidant , inhibits lipid peroxide production in the body, inhibits cholesterol biosynthesis, and has antioxidant and anticancer effects. Let's learn about its antioxidant properties and how to analyze chlorogenic acid in apples using Merck's HPLC analytical column.

Microscopic observation method for observing the structure of emulsions in cosmetics

• An emulsion is a state in which two immiscible liquids are dispersed in a certain ratio, one in the form of small droplets, into the other. Polarizing microscopes are used to observe the emulsion structure in cosmetics.

• Nikon polarizing microscopes are microscopes that allow you to examine the optical properties of a sample by passing light through it. This article introduces the principles of polarizing observation, which allows you to observe emulsion structures.

The solution to permanent gas analysis

• Permanent gas analysis including CO/CO2 in just 10 minutes without cryogenic cooling 
• Rapid separation of permanent gas/light hydrocarbon mixtures
• Excellent compatibility with most GC detectors - Low column bleed

• Rapid stabilization with pre-conditioning (within 30 minutes )

Antibody Selection Guide

• Choosing the appropriate antibody for the experimental purpose is the basis of research.
• Incorrect antibody selection will result in no results or incorrect results.

Protein identification using enzyme-linked immunosorbent assay

• ELISA (Enzyme-Linked Immunosorbent Assay) : This is a method of labeling an antibody (or antigen) with an enzyme, using the enzyme activity as an indicator to check the strength of the antigen-antibody reaction, and quantitatively measuring the antigen (or antibody) through this.

• ELISA is a very basic experimental method in the field of life sciences. It has the advantage of being very sensitive and safe, with a short analysis time.

Research on aging and cancer using antibodies

• Reactive oxygen species (ROS) generated by radiation, smoking, inflammation, etc. affect DNA, proteins, enzymes, etc., causing damage to cells and tissues.

• When the balance between these damages and the rate of repair and removal of damage is broken, lifestyle-related diseases such as arteriosclerosis and hyperlipidemia, cancer, or aging occur.

Protein detection using a Western blot detection kit

Chemiluminescence?

• This is a phenomenon in which electromagnetic radiation is emitted during a chemical reaction, and is generated by oxidation reactions in ultraviolet, visible, or infrared light.
• Radiation can be seen as the transfer of oxidation energy to molecules, which then lose their excitation energy by emitting light of a specific wavelength.

• The luminescence of living organisms such as fireflies and bacteria occurs when luciferin is oxidized by an enzyme called luciferase. This chemiluminescence within living organisms is specifically called bioluminescence.