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Is the SmartDrop better than Nanodrop?

We will analyse both spectrometers for:

Microvolume Analyses of DNA, 
RNA, & Proteins
Nucleic  Acids

Results are in favor of the SmartDrop

• Quicker & accurate results from a sample droplet
• Touch screen control panel, no PC or software required
• Easier Built-in printer and cuvette port for OD600 readings
• XF model includes fluorometer for sensitive DNA 

The Accuris SmartDrop series nano spectrophotometers provide quicker 
eliminates the need for dilutions, providing more accurate results than Nanodrop 

A full color, 7”touchscreen with icon-driven menus and preprogrammed 
protocols gets users up and running quickly. No external computer is required.
Each unit features a quartz pedestal onto which a drop of sample is placed. 
for measurement. DNA, RNA and protein concentrations and purity 
numbers are displayed in a matter of seconds. The resulting data can be 
printed, saved to the SmartDrop’s onboard memory or exported via USB as 
SmartDrop models include an integrated printer for 
instantaneous documentation of results. For OD600 readings, each model 
includes a cuvette port and two optical glass cuvettes. 

Three SmartDrop models are available to meet a range of applications and budgets. 
The SmartDrop L is the aorable choice for laboratories
needing to determine nucleic acid and protein concentrations 
and purity of samples. The LED light source and silicon photocell 
sensor provide readings at 260 and 280nm. Samples from 
1.0 to 2.0µl are loaded directly on the pedestal. Results are 
provided in less than 6 seconds. The software automatically 
calculates and displays 260/280 ratios. 
SmartDrop L

 Nano Drop is stretched into a liquid column Integrated printer for results documentation Cuvette port for OD600 readings
Only a small drop of sample needed

Fixed 0.5mm path length, detect up to 2500ng/ul of dsDNA
A full spectrum UV-Vis spectrophotometer, SmartDrop X 
requires 0.5 to 2.0µl of sample. In addition to nucleic acid 
and protein calculations, the software has preset programs 
for BCA, Bradford and Lowry assays. A full spectrum 
analysis can be performed in about 6 seconds, aiding in the
identication of unknowns.

The long life Xenon lamp requires no warm up and is 
paried with a highly sensitive CCD detector. To provide 
the most accurate results, the SmartDrop X utilizes 2 path 
This top of the line spectrophotometer can perform not 
only UV-Vis readings in the range of 200-800nm

We tested 3 instruments
  1. Nanodrop

  2. SmartDrop X 

  3. SmartDrop XF

acids, proteins, and various colorimetric assays. 
For more accurate and selective quantitation of nucleic acids 
and proteins, the integrated uorometer can measure sample 
concentrations as low as 0.5 pg/µl (dsDNA). The blue light 
channel (460nm) is useful for detection of dyes such as 
PicoGreen, RiboGreen, GFP and uorescein. UV, green, and 
red channel models are available upon request. 
SmartDrop X 

 Full-spectrum absorbance scans from 200 to 800nm
and calculations of 260/280 and 260/230 ratios
 Long-life Xenon lamp and linear array CCD detector
 Auto-ranging path lengths (0.2mm and 1.0mm) 
 Detect up to 4,500 ng/µl of dsDNA without dilution
SmartDrop XF - Spectrophotometer + Fluorometer
 Full-spectrum absorbance scanning and calculations of 
260/280 and 260/230 ratios
 Long-life Xenon lamp with linear array CCD detector
 Auto-ranging path lengths (0.05mm, 0.2mm and 
 Detect up to 15,000ng/µl of dsDNA without dilution 

Absorbance range
Absorbance precision
Lower limit of detection
Upper limit of detection
Absorbance stability
Absorbance repeatibility
Detection time
Absorbance range
Absorbance precision

3.6 kg / 7.9 lbs
USB for data export
SmartDrop L (NS1000)
Ordering Information
* Use part number “-E” to indicate 240V input and specify required plug type.
** Standard model includes blue channel. UV, green, & red channels available.
Accuris Instruments
SmartDrop™ L Nano Spectrophotometer, 115V
SmartDrop™ X Nano Spectrophotometer, 115V
SmartDrop™ XF Nano Spectrophotometer, 115V
High Sensitivity DNA Quantitation Kit, 100 assays
Broad Range dsDNA Quantitation Kit, 100 assays
Additional Standard-Size Cuvettes, pack of 2 
0.5ml Fluorescence Detection Tubes, pack of 250
NS1000-PA Extra Paper Roll for SmartDrop internal printer, pack of 3

NS1000-E SmartDrop™ L Nano Spectrophotometer, 230V $5,800.00 
NS1010-E SmartDrop™ X Nano Spectrophotometer, 230V $10,990.00 
NS1020-E SmartDrop™ XF Nano Spectrophotometer, 230V $12,990.00 
NS1020-HS-100 High Sensitivity DNA Quantification Kit, 100 assays $165.00 
NS1020-BR-100 Broad Range dsDNA Quantification Kit, 100 assays $150.00 
NS1020-T 0.5mL Fluorescence Detection Tubes, pack of 250 $55.00 
NS1000-C Additional Standard-Size Cuvettes, pack of 2 $50.00 
NS1000-PA Extra paper roll for SmartDrop internal printer, Pk 3 $40.00 

Internal Reference: YF-PA26408